After undergoing chemotherapy to treat his leukaemia , a 46 - year - old adult male pick up a bone marrow transplanting from his sister , who fortunately was observe to be a equal . But not long after the mathematical process the recipient experience , for the first time in his life , an allergic reaction to kiwi fruits . It appears that his sister ’s allergic reaction to the fruit was transferred to him along with her off-white marrow .
While this is not the first time an allergy has been transferred like this , according to the authors of a new study , it is the first prison term that researchers have been able to conclusively prove that the allergic reaction was due to the donor ’s cell . The shell is cover in theJournal of the European Academy of Dermatology and Venereology .
When patients undergo intensive treatment for piercing lymphocytic leukemia , thehigh doses of chemotherapyused to defeat the cancer cells also destroys the bone bone marrow mobile phone . These let in a specific stem cell , known as ahematopoietic stem prison cell , which divide and gives wage increase to every type of cell found in your blood , from red line jail cell to livid blood cell . This imply that the leukaemia patients then have to undergo a osseous tissue marrow transplant from a donor in social club to have their bones repopulated with the hemopoietic stem cells .
Allergies are caused when white blood cells produce antibodies in an adverse immune response to a harmless substance , such as pollen , nut case , or in this case , apteryx fruit . Previous bone marrow transplantation have shared allergies from a donor to the recipient , but scientists were not sure if this was because they had plainly transferred some of the antibody to the specific pith , and that over time these would be break down and the receiver will lose the allergic reaction .
But this time round , the researcher were able to hunt where the antibody that were reacting to the kiwi fruit really originated from using a technique known asfluorescencein situhybridization . This allowed the researchers to trace the blood of the antibody to the two X - chromosome in the male affected role ( who ’s own cells are all XY ) , which means that they had to come from his sister who donate her bone marrow , and thus meaning that the allergy originated in her hematopoietic stem cells .
While allergic reaction transferee from bone pith transplants is a rare happening , this is the first meter that this has been conclusively proven . The study opens the door to more investigations into how allergic reaction can be spread out and potentially treated , by looking into patient ' ivory heart and the hematogenic cubicle contain within .
